Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | FGF23 | Q9GZV9 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31046315 | 1.00 | ALDH1A1 (0.47) | ALDH1A1FGF23LMNAL3MBTL1USP2 | |
| SCHEMBL20597363 | 0.78 | FGF23 (0.61) | ALDH1A1FGF23LMNAL3MBTL1USP2 | |
| SCHEMBL19880469 | 0.77 | ALDH1A1 (0.49) | ALDH1A1FGF23LMNAL3MBTL1USP2 | |
| SCHEMBL19769027 | 0.77 | ALDH1A1 (0.49) | ALDH1A1FGF23LMNAL3MBTL1USP2 | |
| SCHEMBL8486922 | 0.76 | NAPRT (0.48) | NAPRTAMY1AMEN1NPC1MAPT | |
| SCHEMBL8486928 | 0.76 | NAPRT (0.48) | NAPRTAMY1AMEN1NPC1MAPT | |
| SCHEMBL1202413 | 0.76 | ALDH1A1 (0.47) | ALDH1A1FGF23LMNAL3MBTL1HPGD | |
| SCHEMBL1576671 | 0.76 | TRIM24 (0.57) | ALDH1A1FGF23LMNAL3MBTL1USP2 | |
| SCHEMBL2120978 | 0.76 | FGF23 (0.55) | ALDH1A1FGF23LMNAUSP2HPGD | |
| SCHEMBL1202412 | 0.76 | ALDH1A1 (0.47) | ALDH1A1FGF23LMNAL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151833-A1 | SPIRO DERIVATIVES AS M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-07-18 | — | — | WO | disclosed |