Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298580 | 0.95 | KDM4E (0.50) | KDM4EMAPK1HIF1APAOXFOLH1 | |
| SCHEMBL21534451 | 0.86 | C3AR1 (0.36) | KDM4EMAPK1HIF1APAOXFOLH1 | |
| SCHEMBL24864551 | 0.79 | KDM4E (0.52) | KDM4EMAPK1HIF1APAOXFOLH1 | |
| SCHEMBL13133644 | 0.79 | KDM4E (0.52) | KDM4EMAPK1HIF1APAOXFOLH1 | |
| SCHEMBL17951698 | 0.78 | ADH1B (0.53) | SIRT6SIRT1ZDHHC7DPP7ADH1B | |
| SCHEMBL17210488 | 0.76 | GSR (0.42) | PAOXFOLH1SIRT6SIRT1DPP7 | |
| SCHEMBL14932592 | 0.74 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXFOLH1 | |
| SCHEMBL11887166 | 0.74 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXFOLH1 | |
| SCHEMBL10408291 | 0.74 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXFOLH1 | |
| SCHEMBL14932573 | 0.74 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151890-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-07-18 | — | — | WO | disclosed |