Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18927592 | 0.80 | RIPK1 (0.56) | RIPK1HSP90AA1CHRNA7CHRNB2CHRNB4 | |
| SCHEMBL18711396 | 0.72 | POLB (0.61) | RIPK1KMT2AMEN1POLBTSHR | |
| SCHEMBL4657697 | 0.71 | RIPK1 (0.47) | RIPK1HSP90AA1KMT2AMEN1POLB | |
| SCHEMBL4657693 | 0.71 | RIPK1 (0.47) | RIPK1HSP90AA1KMT2AMEN1POLB | |
| SCHEMBL22300290 | 0.69 | HRH3 (0.56) | RAB9ATSHR | |
| SCHEMBL18702108 | 0.68 | RIPK1 (0.71) | RIPK1POLB | |
| SCHEMBL9102827 | 0.68 | MEN1 (0.53) | RIPK1KMT2AMEN1POLBTSHR | |
| SCHEMBL7133590 | 0.67 | RIPK1 (0.54) | RIPK1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL25327358 | 0.67 | RIPK1 (0.44) | RIPK1HSP90AA1 | |
| SCHEMBL24133882 | 0.66 | RIPK1 (0.41) | RIPK1CHRNA7CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064923-A9 | COVALENT, CHEMOGENETIC ACTIVATORS FOR K2P POTASSIUM CHANNELS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-18 | — | — | WO | disclosed |