Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18828597 | 0.83 | MAOA (0.50) | MEN1KMT2ATSHRRIPK1 | |
| SCHEMBL3188035 | 0.81 | NR1H2 (0.56) | RIPK1ABCB1 | |
| SCHEMBL12668388 | 0.81 | NR1H2 (0.56) | RIPK1ABCB1 | |
| SCHEMBL3188043 | 0.81 | NR1H2 (0.56) | RIPK1ABCB1 | |
| SCHEMBL10002512 | 0.80 | RIPK1 (0.64) | MEN1KMT2ARIPK1 | |
| SCHEMBL18711396 | 0.79 | POLB (0.61) | MEN1KMT2ATSHRRIPK1KIF11 | |
| SCHEMBL12184218 | 0.79 | RIPK1 (0.58) | MEN1KMT2ARIPK1 | |
| SCHEMBL27672000 | 0.79 | RIPK1 (0.58) | MEN1KMT2ARIPK1 | |
| SCHEMBL4657693 | 0.79 | RIPK1 (0.47) | MEN1KMT2ARIPK1P2RX7POLB | |
| SCHEMBL4657697 | 0.79 | RIPK1 (0.47) | MEN1KMT2ARIPK1P2RX7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030672-A1 | AZIRIDINE COMPOUNDS, METHODS OF PREPARATION AND REACTIONS THEREOF | DREXEL UNIVERSITY (US) | 1995-11-16 | — | — | WO | disclosed |
| US-5434261-A | Benzo-fused lactams promote release of growth hormone | MERCK & CO., INC. (US) | 1995-07-18 | — | — | US | disclosed |