SCHEMBL2933654

SCHEMBL2933654

O=C(O)N(S)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.50
TRPM8 Q7Z2W7 2/20 0.42
ALDH1A1 P00352 6/20 0.41
NPC1 O15118 2/20 0.41
HTT P42858 2/20 0.41
RAB9A P51151 2/20 0.41
GLA P06280 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 2/20 0.41
POLB P06746 1/20 0.41
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1681249 0.80 NPSR1 (0.46) NPSR1TRPM8ALDH1A1NPC1HTT
SCHEMBL14921002 0.80 NPSR1 (0.46) NPSR1TRPM8ALDH1A1NPC1HTT
SCHEMBL27691218 0.78 EGFR (0.43) ALDH1A1SMN1; SMN2
SCHEMBL4047678 0.77 NPSR1 (0.43) NPSR1TRPM8ALDH1A1NPC1HTT
SCHEMBL27675939 0.75 NPSR1 (0.46) NPSR1TRPM8ALDH1A1NPC1HTT
SCHEMBL11372476 0.75 LMNA (0.42) NPSR1TRPM8ALDH1A1NPC1HTT
SCHEMBL28248375 0.75 L3MBTL1 (0.46) NPSR1TRPM8ALDH1A1GLAKMT2A
SCHEMBL5353973 0.73 MEN1 (0.56) NPSR1ALDH1A1NPC1RAB9AKMT2A
SCHEMBL891832 0.72 NPSR1 (0.55) NPSR1TRPM8ALDH1A1NPC1HTT
SCHEMBL19778 0.72 NPSR1 (0.70) NPSR1TRPM8ALDH1A1NPC1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563384-B1 URACIL DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2001-10-04 EP claimed
EP-0563384-A1 URACIL DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1993-10-06 EP claimed
JP-56115704-A None JP disclosed
US-20250368783-A1 DITHIOL-BASED POLYMERS AND CYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY (US) 2025-12-04 US disclosed
WO-2023244535-A1 DITHIOL-BASED POLYMERS AND CYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2023-12-21 WO disclosed
WO-2019167814-A1 METHOD FOR PRODUCING MERCAPTOPHENOL COMPOUND AND INTERMEDIATE OF SAID COMPOUND クミアイ化学工業株式会社 2019-09-06 WO disclosed
EP-2229391-A1 PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE Cancer Research Technology Limited (GB) 2010-09-22 EP disclosed
WO-2009077766-A1 PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2009-06-25 WO disclosed
EP-1178039-B1 Derivatives of phenyl(thio)urea and phenyl(thio)carbamate fungicides BAYER CROPSCIENCE SA (FR) 2007-04-11 EP disclosed
EP-1178039-B1 Derivatives of phenyl(thio)urea and phenyl(thio)carbamate fungicides BAYER CROPSCIENCE SA (FR) 2007-04-11 EP disclosed
US-6696487-B2 FOR COMBATING THE PHYTOPATHOGENIC FUNGI OF CROPS BAYER CROPSCIENCE S.A. (FR) 2004-02-24 US disclosed
EP-1178039-A1 Derivatives of phenyl(thio)urea and phenyl(thio)carbamate fungicides AVENTIS CROPSCIENCE S.A. (FR) 2002-02-06 EP disclosed
EP-1178039-A1 Derivatives of phenyl(thio)urea and phenyl(thio)carbamate fungicides AVENTIS CROPSCIENCE S.A. (FR) 2002-02-06 EP disclosed
EP-0563384-B1 URACIL DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2001-10-04 EP disclosed
US-5356863-A Herbicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1994-10-18 US disclosed
EP-0563384-A1 URACIL DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1993-10-06 EP disclosed
JP-S56115704-A FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL CULTIVATION ASAHI CHEM IND CO LTD 1981-09-11 JP disclosed
EP-0007806-B1 N-SULFENYL DERIVATIVES OF DI(CARBAMIC ACID ESTERS) AND VULCANIZABLE RUBBER COMPOSITIONS CONTAINING THEM MONSANTO COMPANY (US) 1981-08-26 EP disclosed
EP-0007806-A1 N-Sulfenyl derivatives of di(carbamic acid esters) and vulcanizable rubber compositions containing them MONSANTO COMPANY (US) 1980-02-06 EP disclosed
US-4165310-A N-SULFENYL DERIVATIVES OF DI(CARBAMIC ACID ESTERS) USED AS PREMATURE VULCANIZING INHIBITORS MONSANTO COMPANY (US) 1979-08-21 US disclosed