Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.37 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146070 | 1.00 | CTSK (0.39) | CTSKIDH1IRAK4SOS2CTSS | |
| SCHEMBL22230336 | 1.00 | CTSK (0.39) | CTSKIDH1IRAK4SOS2CTSS | |
| Hydrochloric Acid SCHEMBL22230342 | 0.98 | CTSK (0.38) | CTSKIDH1IRAK4SOS2CTSS | |
| Hydrochloric Acid SCHEMBL22230340 | 0.98 | CTSK (0.38) | CTSKIDH1IRAK4SOS2CTSS | |
| SCHEMBL179277 | 0.84 | HSD11B1 (0.41) | CTSKIDH1SOS2CTSSADORA2A | |
| SCHEMBL20738618 | 0.81 | IDH1 (0.38) | CTSKIDH1SOS2CTSSADORA2A | |
| SCHEMBL20989227 | 0.81 | IDH1 (0.38) | CTSKIDH1SOS2CTSSADORA2A | |
| SCHEMBL17574520 | 0.80 | CTSS (0.36) | CTSKIDH1IRAK4SOS2CTSS | |
| Hydrochloric Acid SCHEMBL1111090 | 0.79 | TAAR1 (0.36) | CTSKIDH1IRAK4SOS2CTSS | |
| SCHEMBL522063 | 0.79 | CYP1A2 (0.38) | IRAK4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |