SCHEMBL2933720

SCHEMBL2933720

COC1(OC)CCC(COS(C)(=O)=O)CC1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MMP9 P14780 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9908266 0.84
SCHEMBL1710773 0.83 SCN9A (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL29835805 0.81 KDM4E (0.33) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL16093887 0.81 SCN9A (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7705221 0.80 USP2 (0.42) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL14414058 0.80 USP2 (0.42) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL1062380 0.80
SCHEMBL17061880 0.78 SCN9A (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL19601345 0.78 KDM4E (0.31) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL121125 0.76 LMNA (0.39) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197793-B2 Methods of radiofluorination of biologically active vectors GE HEALTHCARE AS (NO) 2012-06-12 US disclosed
EP-1601384-B1 METHODS OF RADIOFLUORINATION OF BIOLOGICALLY ACTIVE VECTORS GE HEALTHCARE AS (NO) 2010-09-22 EP disclosed
US-20100068139-A1 Methods of radiofluorination of biologically active vectors GE HEALTHCARE AS (NO) 2010-03-18 US disclosed
CN-100586485-C Radiofluorination method of bioactive carrier AMERSHAM HEALTH AS 2010-02-03 CN disclosed
CN-1758925-A Radiofluorination method of bioactive carrier AMERSHAM HEALTH AS (NO) 2006-04-12 CN disclosed
EP-1601384-A1 METHODS OF RADIOFLUORINATION OF BIOLOGICALLY ACTIVE VECTORS Amersham Health AS (NO) 2005-12-07 EP disclosed
WO-2004080492-A1 METHODS OF RADIOFLUORINATION OF BIOLOGICALLY ACTIVE VECTORS AMERSHAM HEALTH AS (NO) 2004-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100068139-A1 Methods of radiofluorination of biologically active vectors DOHH, VGF, HNRNPH3 KDM4E 3414/4885USP2 2522/4885ALDH1A1 1683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.