Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24166309 | 0.79 | SIRT3 (0.50) | SIRT3TDP1ABL1 | |
| SCHEMBL18033428 | 0.75 | PRSS1 (0.33) | PRSS1PRSS2PRSS3 | |
| SCHEMBL29364820 | 0.72 | HPGD (0.47) | TDP1ABL1 | |
| SCHEMBL1667344 | 0.72 | HPGD (0.47) | TDP1ABL1 | |
| SCHEMBL8578654 | 0.72 | SMN1; SMN2 (0.45) | SIRT3TDP1ABL1 | |
| SCHEMBL15473326 | 0.72 | — | — | |
| SCHEMBL27725504 | 0.71 | ABL1 (0.38) | SIRT3TDP1P2RX7ABL1 | |
| SCHEMBL24144945 | 0.71 | SYK (0.39) | — | |
| Hydrochloric Acid SCHEMBL22042768 | 0.69 | SYK (0.38) | — | |
| Hydrochloric Acid SCHEMBL22042723 | 0.69 | PRSS1 (0.31) | PRSS1PRSS2C1SPRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | UNIMATEC CO., LTD. (JP) | 2024-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | CNOT1, NUDT1, XRN2 | SIRT3 1714/4885TDP1 208/4885UBE2T 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.