Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23384767 | 0.85 | TACR1 (0.45) | GAATACR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL27229801 | 0.83 | TACR1 (0.49) | GAATACR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10296153 | 0.80 | LMNA (0.45) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL21254127 | 0.78 | ALDH1A1 (0.74) | ALDH1A1HTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL29784651 | 0.77 | DYRK1A (0.43) | GAATACR1SMN1; SMN2 | |
| SCHEMBL24324560 | 0.77 | TACR1 (0.41) | GAATACR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7529534 | 0.76 | NPC1 (0.65) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23384717 | 0.75 | NPC1 (0.52) | GAATACR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1274028 | 0.75 | TACR1 (0.50) | TACR1ALDH1A1HTTLMNAAOC3 | |
| SCHEMBL6289037 | 0.74 | TACR1 (0.60) | TACR1ALDH1A1HTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |