Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 9/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 8/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 8/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12304435 | 0.84 | ADORA2A (0.46) | ADORA2AADORA2BADORA1CDK1CCNB1 | |
| SCHEMBL22326755 | 0.79 | ADORA2A (0.61) | ADORA2AADORA2BADORA1ADACDK1 | |
| SCHEMBL18510377 | 0.77 | CDK1 (0.51) | ADORA2AADORA2BADORA1ADACDK1 | |
| SCHEMBL25656618 | 0.77 | ADORA2A (0.51) | ADORA2AADORA2BADORA1ADACDK1 | |
| SCHEMBL19661692 | 0.75 | ADORA2A (0.64) | ADORA2AADORA2BADORA1CDK1CCNB1 | |
| SCHEMBL24896143 | 0.73 | YTHDC1 (0.51) | ADORA2AADORA1CDK1CDK2KDM4E | |
| SCHEMBL18510395 | 0.71 | CDK1 (0.49) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL23199830 | 0.71 | SLC40A1 (0.33) | GRM5GRM1 | |
| SCHEMBL26354676 | 0.70 | CDK1 (0.65) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL24922789 | 0.69 | CDK1 (0.37) | ADORA2AADORA2BADORA1ADACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240240182-A1 | HUMAN CHROMOSOME 9 OPEN READING FRAME 72 (C9ORF72) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF | BANK OF AMERICA, N.A. | 2024-07-18 | — | — | US | disclosed |