Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 4/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 8/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29122941 | 0.91 | CFD (0.40) | CFDKDM4EALDH1A1GLAGAA | |
| SCHEMBL29339677 | 0.91 | CFD (0.39) | CFDICMT | |
| SCHEMBL29340041 | 0.90 | CFD (0.46) | CFDKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29344426 | 0.90 | CFD (0.35) | CFDKDM4EALDH1A1GLAGAA | |
| SCHEMBL29121929 | 0.88 | CFD (0.40) | CFDKDM4EALDH1A1GLAGAA | |
| SCHEMBL29340617 | 0.87 | CFD (0.43) | CFDKDM4EALDH1A1GLAGAA | |
| SCHEMBL29340322 | 0.87 | CFD (0.43) | CFDALDH1A1ICMTTBXAS1 | |
| SCHEMBL29340055 | 0.87 | CFD (0.40) | CFDKDM4EALDH1A1GLAGAA | |
| SCHEMBL23219007 | 0.84 | CFD (0.47) | CFDKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29852422 | 0.84 | CFD (0.47) | CFDKDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | KLK5, KLK1, KLKB1 | CFD 3529/4885KDM4E 851/4885ALDH1A1 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.