Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 9/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123049 | 0.91 | CFD (0.40) | CFDICMTDPP4TBXAS1TSPO | |
| SCHEMBL29339681 | 0.91 | ICMT (0.42) | CFDICMTPLAUF2F10 | |
| SCHEMBL29344432 | 0.91 | CFD (0.36) | CFDICMTDPP4PLAUF2 | |
| SCHEMBL29340041 | 0.90 | CFD (0.46) | CFDICMTTBXAS1F2F10 | |
| SCHEMBL29340617 | 0.89 | CFD (0.43) | CFDICMTDPP4TBXAS1ALDH1A1 | |
| SCHEMBL29340320 | 0.87 | CFD (0.43) | CFDICMTTBXAS1ALDH1A1 | |
| SCHEMBL29340323 | 0.86 | CFD (0.42) | CFDICMTDPP4TBXAS1 | |
| SCHEMBL29123387 | 0.86 | CFD (0.40) | CFDICMTTBXAS1PLAUTSPO | |
| SCHEMBL29340316 | 0.86 | CFD (0.40) | CFDICMTDPP4TBXAS1ALDH1A1 | |
| SCHEMBL29340826 | 0.85 | CFD (0.43) | CFDICMTTBXAS1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | KLK5, KLK1, KLKB1 | CFD 3529/4885ICMT 4826/4885DPP4 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.