Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29342485 | 0.86 | MEN1 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL27162947 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL29222044 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL27163189 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL29342224 | 0.78 | NPC1 (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL27163231 | 0.75 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1NPSR1GLA | |
| SCHEMBL29343980 | 0.73 | EED (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL3642333 | 0.72 | TSHR (0.65) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL948640 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL8117183 | 0.71 | BRD4 (0.52) | SMN1; SMN2RAB9AALDH1A1CYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | UACA, ADCYAP1R1, ADCY1 | SMN1; SMN2 4377/4885NPC1 496/4885RAB9A 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.