Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.43 |
| ▸ | MARS1 | P56192 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538645 | 0.84 | MAPT (0.54) | MAPTGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12004538 | 0.84 | GAA (0.54) | MAPTGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8037982 | 0.83 | KDM4E (0.54) | MAPTGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31072837 | 0.83 | HDAC8 (0.57) | MAPTGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29343400 | 0.83 | AURKA (0.40) | MAPTGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31072780 | 0.82 | KMT2A (0.50) | MAPTGAAALDH1A1PTGER4HPGD | |
| SCHEMBL29343397 | 0.82 | KMT2A (0.50) | MAPTGAAALDH1A1PTGER4HPGD | |
| SCHEMBL4539438 | 0.80 | ALDH1A1 (0.52) | MAPTGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4308882 | 0.79 | ABL1 (0.51) | MAPTGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28545286 | 0.79 | ALDH1A1 (0.52) | MAPTGAAKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |