Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 5/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 4/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423987 | 0.85 | NQO2 (0.39) | NCF1KCNA3ALOX5APFEN1HTR1B | |
| SCHEMBL6041625 | 0.83 | PKM (0.35) | NCF1KCNA3ALOX5APFEN1HTR1B | |
| SCHEMBL6041616 | 0.83 | L3MBTL1 (0.34) | NCF1KCNA3ALOX5APFEN1HTR1B | |
| SCHEMBL29937490 | 0.82 | KCNA3 (0.34) | NCF1KCNA3ALOX5APFEN1HTR1B | |
| SCHEMBL6041493 | 0.80 | CDC25B (0.40) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL6042018 | 0.78 | PDE4A (0.36) | KCNA3ALOX5APFEN1ALDH1A1HPGD | |
| SCHEMBL26197489 | 0.77 | CYP1A2 (0.48) | CYP1A2CYP2A6HTR1BHTR1DALDH1A1 | |
| SCHEMBL4419587 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HPGDLMNAHTTSMN1; SMN2 | |
| SCHEMBL25325320 | 0.75 | MAPT (0.46) | ALDH1A1HPGDLMNAMAPTMAPK1 | |
| SCHEMBL6042263 | 0.75 | PDE10A (0.35) | ALOX5APFEN1ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | KRAS, NRAS, HRAS | CYP1A2 4576/4885CYP2A6 3523/4885NCF1 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.