Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989199 | 0.82 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL11084756 | 0.82 | TAAR1 (0.37) | ADRA2AADRA2BADRA2CALDH1A1SMN1; SMN2 | |
| SCHEMBL3431154 | 0.81 | TAAR1 (0.55) | LMNATAAR1SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL5330393 | 0.79 | SLC6A2 (0.40) | ADRA2AADRA2BADRA2CALDH1A1SMN1; SMN2 | |
| SCHEMBL22097765 | 0.77 | TDP1 (0.34) | ADRA2AADRA2BADRA2CALDH1A1SMN1; SMN2 | |
| SCHEMBL18432450 | 0.76 | GRIA4 (0.40) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL10195708 | 0.75 | HDAC8 (0.36) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL16979038 | 0.74 | ESR1 (0.44) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL9397889 | 0.74 | ALDH1A1 (0.44) | ADRA2AADRA2BADRA2CHDAC8HDAC6 | |
| SCHEMBL18714383 | 0.74 | ESR1 (0.46) | ADRA2AADRA2BADRA2CHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |