SCHEMBL29346014

SCHEMBL29346014

CO/N=C(\Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 10/20 0.61
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
AKR1B1 P15121 1/20 0.47
HDAC3 O15379 3/20 0.44
HDAC4 P56524 3/20 0.44
HDAC1 Q13547 3/20 0.44
HDAC7 Q8WUI4 3/20 0.44
HDAC2 Q92769 3/20 0.44
HDAC10 Q969S8 3/20 0.44
HDAC11 Q96DB2 3/20 0.44
HDAC8 Q9BY41 3/20 0.44
HDAC6 Q9UBN7 3/20 0.44
HDAC9 Q9UKV0 3/20 0.44
HDAC5 Q9UQL6 3/20 0.44
TSHR P16473 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HIF1A Q16665 1/20 0.43
THRB P10828 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11888718 1.00 CTBP2 (0.61) CTBP2CES2CES1AKR1B1HDAC3
SCHEMBL7866062 0.89 CTBP2 (0.52) CTBP2CES2CES1AKR1B1HDAC3
SCHEMBL31264429 0.86 CTBP2 (0.67) CTBP2HDAC3HDAC4HDAC1HDAC7
SCHEMBL31264433 0.84 CTBP2 (0.65) CTBP2HDAC3HDAC4HDAC1HDAC7
SCHEMBL31264409 0.84 CTBP2 (0.65) CTBP2HDAC3HDAC4HDAC1HDAC7
SCHEMBL31264460 0.82 CTBP2 (0.52) CTBP2HDAC3HDAC4HDAC1HDAC7
SCHEMBL31264413 0.80 CTBP2 (0.48) CTBP2HDAC3HDAC4HDAC1HDAC7
SCHEMBL7875372 0.80 CTBP2 (0.50) CTBP2CES2CES1AKR1B1HDAC3
SCHEMBL11110698 0.80 CTBP2 (0.59) CTBP2CES2CES1AKR1B1ALDH1A1
SCHEMBL7875369 0.80 CTBP2 (0.50) CTBP2CES2CES1AKR1B1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024251301-A1 GSPT1 PROTEIN DEGRADER CONTAINING OXIME STRUCTURE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国药科大学 2024-12-12 WO disclosed
CN-119080738-A GSPT1 protein degradation agent containing oxime structure and preparation method and application thereof 中国药科大学 2024-12-06 CN disclosed
US-20240241437-A1 SEMICONDUCTOR PHOTORESIST COMPOSITION AND METHOD OF FORMING PATTERNS USING THE COMPOSITION SAMSUNG SDI CO., LTD. (KR) 2024-07-18 US disclosed
US-20240241437-A1 SEMICONDUCTOR PHOTORESIST COMPOSITION AND METHOD OF FORMING PATTERNS USING THE COMPOSITION SAMSUNG SDI CO., LTD. (KR) 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240241437-A1 SEMICONDUCTOR PHOTORESIST COMPOSITION AND METHOD OF FORMING PATTERNS USING THE COMPOSITION BPNT1, NISCH, LCP1 CTBP2 1620/4885CES2 2173/4885CES1 3134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.