SCHEMBL7875372

SCHEMBL7875372

CON=C(Cc1ccccc1)C(C)=NO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 8/20 0.50
HDAC3 O15379 3/20 0.38
HDAC4 P56524 3/20 0.38
HDAC1 Q13547 3/20 0.38
HDAC7 Q8WUI4 3/20 0.38
HDAC2 Q92769 3/20 0.38
HDAC10 Q969S8 3/20 0.38
HDAC11 Q96DB2 3/20 0.38
HDAC8 Q9BY41 3/20 0.38
HDAC6 Q9UBN7 3/20 0.38
HDAC9 Q9UKV0 3/20 0.38
HDAC5 Q9UQL6 3/20 0.38
MAPT P10636 1/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
ALDH1A1 P00352 1/20 0.37
MGLL Q99685 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
AKR1B1 P15121 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7875369 1.00 CTBP2 (0.50) CTBP2HDAC3HDAC4HDAC1HDAC7
SCHEMBL27570436 0.88 CTBP2 (0.53) CTBP2MAPTCA1CA2ALDH1A1
SCHEMBL3391716 0.85 CTBP2 (0.62) CTBP2CA1CA2CES2CES1
SCHEMBL7866062 0.84 CTBP2 (0.52) CTBP2HDAC3HDAC4HDAC1HDAC7
SCHEMBL29346014 0.80 CTBP2 (0.61) CTBP2HDAC3HDAC4HDAC1HDAC7
SCHEMBL11888718 0.80 CTBP2 (0.61) CTBP2HDAC3HDAC4HDAC1HDAC7
SCHEMBL10177918 0.77 MAPT (0.49) CTBP2MAPTALDH1A1CES2CES1
SCHEMBL19433075 0.77 MAPT (0.49) CTBP2MAPTALDH1A1CES2CES1
SCHEMBL18840218 0.77 MAPT (0.49) CTBP2MAPTALDH1A1CES2CES1
SCHEMBL18840185 0.75 ALDH1A1 (0.43) CTBP2MAPTALDH1A1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1075490-C O-benzyl oxime ether derivatives and their use in crop protection compositions BAYER AG (DE) 2001-11-28 CN disclosed
US-6319925-B1 MICROBICIDAL, ACARICIDAL AND INSECTICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2001-11-20 US disclosed
EP-0848701-B1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS NOVARTIS AG (CH) 2000-05-17 EP disclosed
CN-1189150-A O-benzyl oxime ether derivatives and their use in crop protection compositions NOVATIS LTD (CH) 1998-07-29 CN disclosed
EP-0848701-A1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS Novartis AG (CH) 1998-06-24 EP disclosed
WO-1997001530-A1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS NOVARTIS AG (CH) 1997-01-16 WO disclosed