Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748131 | 1.00 | ALDH1A1 (0.42) | ALDH1A1LMNAALDH3A1ALDH2OPRL1 | |
| SCHEMBL15156486 | 0.80 | TP53 (0.52) | ALDH1A1LMNAALDH3A1ALDH2OPRL1 | |
| SCHEMBL9543551 | 0.74 | OPRL1 (0.48) | ALDH1A1LMNAOPRL1L3MBTL1 | |
| SCHEMBL31748066 | 0.71 | TSHR (0.40) | ALDH1A1LMNATP53TSHRSMN1; SMN2 | |
| SCHEMBL9544593 | 0.69 | OPRL1 (0.50) | ALDH1A1LMNAOPRL1L3MBTL1 | |
| SCHEMBL31729969 | 0.69 | ALDH1A1 (0.41) | ALDH1A1LMNAALDH3A1ALDH2OPRL1 | |
| SCHEMBL9774461 | 0.68 | TDP1 (0.42) | ALDH1A1LMNAALDH3A1ALDH2OPRL1 | |
| SCHEMBL17830714 | 0.67 | PTGDR2 (0.51) | — | |
| SCHEMBL3190305 | 0.67 | CNR1 (0.45) | ALDH1A1LMNATP53MAPTSMN1; SMN2 | |
| SCHEMBL1901777 | 0.66 | ALDH1A1 (0.53) | ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |