SCHEMBL31729969

SCHEMBL31729969

CC1(N2CC=CC(=O)NC2=O)C(=O)N(CC(=O)OCc2ccccc2)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.41
LMNA P02545 3/20 0.41
OPRL1 P41146 8/20 0.39
MAPT P10636 2/20 0.38
ALDH3A1 P30838 2/20 0.36
ALDH2 P05091 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31730088 0.86 ALDH1A1 (0.38) ALDH1A1LMNAOPRL1MAPTGAA
SCHEMBL15156486 0.77 TP53 (0.52) ALDH1A1LMNAOPRL1MAPTALDH3A1
SCHEMBL29347593 0.75 ALDH1A1 (0.38) ALDH1A1LMNAOPRL1MAPTALDH3A1
SCHEMBL9543551 0.73 OPRL1 (0.48) ALDH1A1LMNAOPRL1
SCHEMBL31748131 0.69 ALDH1A1 (0.42) ALDH1A1LMNAOPRL1MAPTALDH3A1
SCHEMBL29347277 0.69 ALDH1A1 (0.42) ALDH1A1LMNAOPRL1MAPTALDH3A1
SCHEMBL9544593 0.68 OPRL1 (0.50) ALDH1A1LMNAOPRL1
SCHEMBL31730106 0.66 ALDH1A1 (0.41) ALDH1A1LMNAOPRL1TSHRGAA
SCHEMBL9541775 0.65 TDP1 (0.51) ALDH1A1LMNAOPRL1MAPTALDH3A1
SCHEMBL9774461 0.65 TDP1 (0.42) ALDH1A1LMNAOPRL1ALDH3A1ALDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 US disclosed
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL ALDH1A1 579/4885LMNA 3163/4885OPRL1 501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.