Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.48 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543551 | 0.91 | OPRL1 (0.48) | OPRL1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL17830714 | 0.79 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL17830713 | 0.76 | USP2 (0.44) | PTGDR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL15156486 | 0.75 | TP53 (0.52) | OPRL1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL9774497 | 0.74 | PTGDR2 (0.48) | OPRL1PTGDR2ALDH1A1 | |
| SCHEMBL9541775 | 0.73 | TDP1 (0.51) | OPRL1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL17830710 | 0.70 | ALDH1A1 (0.64) | ALDH1A1 | |
| SCHEMBL9774461 | 0.69 | TDP1 (0.42) | OPRL1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL29347277 | 0.69 | ALDH1A1 (0.42) | OPRL1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL31748131 | 0.69 | ALDH1A1 (0.42) | OPRL1ALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012786-A1 | INDOLINONE DERIVATIVES | HOWARD HARRY R JR (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5064852-A | Antidiabetic agents; aldose reductase inhibitors | PFIZER INC. (US) | 1991-11-12 | — | — | US | disclosed |