Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560232 | 0.74 | BMPR1B (0.46) | CYP3A4CYP2D6TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL13000004 | 0.74 | BMPR1B (0.49) | CYP3A4CYP2D6TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL29348230 | 0.74 | PRKDC (0.32) | SMN1; SMN2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL13019295 | 0.73 | SMN1; SMN2 (0.40) | CYP3A4CYP2D6TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8136850 | 0.73 | SMN1; SMN2 (0.40) | CYP3A4CYP2D6TSHRSMN1; SMN2CYP11B1 | |
| SCHEMBL23563045 | 0.71 | SIGMAR1 (0.41) | CYP3A4CYP2D6TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL29348208 | 0.71 | CYP11B1 (0.41) | CYP3A4CYP2D6TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL23563044 | 0.71 | SIGMAR1 (0.41) | CYP3A4CYP2D6TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL29348228 | 0.71 | SMN1; SMN2 (0.39) | CYP2D6TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL261618 | 0.68 | CYP3A4 (0.40) | CYP3A4CYP11B1CYP11B2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |