Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350158 | 0.78 | ALOX12 (0.47) | TP53CYP2D6POLBALDH1A1CYP2C9 | |
| SCHEMBL11021537 | 0.76 | HDAC6 (0.42) | CYP11B1CYP11B2HDAC6TP53SLC22A6 | |
| SCHEMBL11021442 | 0.76 | CYP11B1 (0.41) | CYP11B1CYP11B2HDAC6TP53SLC22A6 | |
| SCHEMBL14560232 | 0.73 | BMPR1B (0.46) | CYP3A4CYP2D6ALDH1A1CYP2C9BMPR1B | |
| SCHEMBL13140225 | 0.73 | KMO (0.51) | PIK3CDPIK3R1MTORPOLBHTT | |
| SCHEMBL17807815 | 0.73 | PIK3CD (0.41) | PIK3CDPIK3R1MTORPOLBALDH1A1 | |
| SCHEMBL18237516 | 0.73 | PIK3CD (0.31) | CYP11B1CYP11B2PIK3CDPIK3R1MTOR | |
| SCHEMBL13019295 | 0.72 | SMN1; SMN2 (0.40) | CYP11B1CYP11B2HDAC6CYP3A4CYP2D6 | |
| SCHEMBL29348279 | 0.72 | PDE3B (0.47) | ALDH1A1HTTTSHR | |
| SCHEMBL29348226 | 0.72 | PDE3B (0.47) | ALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |