Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCND2 | P30279 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12411028 | 0.76 | POLB (0.37) | PGRPOLBALDH1A1L3MBTL1CDK4 | |
| SCHEMBL2741639 | 0.74 | POLB (0.36) | PGRPOLBALDH1A1L3MBTL1CDK4 | |
| SCHEMBL27407441 | 0.74 | POLB (0.40) | PGRPOLBALDH1A1L3MBTL1CDK4 | |
| SCHEMBL11920593 | 0.74 | POLB (0.36) | PGRPOLBALDH1A1L3MBTL1CDK4 | |
| SCHEMBL9354143 | 0.68 | IDH1 (0.37) | POLBALDH1A1CYP3A4 | |
| SCHEMBL21948296 | 0.68 | LMNA (0.34) | PGRPOLBALDH1A1L3MBTL1 | |
| SCHEMBL21476005 | 0.67 | POLB (0.33) | POLBALDH1A1 | |
| SCHEMBL21960472 | 0.67 | ALDH1A1 (0.32) | PGRPOLBALDH1A1L3MBTL1 | |
| SCHEMBL18804578 | 0.64 | ALDH1A1 (0.36) | PGRPOLBALDH1A1L3MBTL1CDK4 | |
| SCHEMBL29941410 | 0.63 | CA12 (0.57) | POLBALDH1A1L3MBTL1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |