Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25C | P30307 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13303071 | 0.78 | LMNA (0.42) | LMNAMCOLN3ALDH1A1L3MBTL1CDC25A | |
| SCHEMBL21960472 | 0.78 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1PGRPOLBP2RX3 | |
| SCHEMBL13325663 | 0.78 | ALDH1A1 (0.33) | LMNAMCOLN3ALDH1A1L3MBTL1CDC25A | |
| SCHEMBL29348235 | 0.68 | PGR (0.36) | ALDH1A1L3MBTL1PGRPOLB | |
| SCHEMBL18804578 | 0.67 | ALDH1A1 (0.36) | LMNAMCOLN3ALDH1A1L3MBTL1PGR | |
| SCHEMBL18937487 | 0.64 | BRD4 (0.35) | LMNAMCOLN3ALDH1A1L3MBTL1CDC25A | |
| SCHEMBL23163270 | 0.62 | SLC9A1 (0.38) | LMNAMCOLN3ALDH1A1L3MBTL1POLB | |
| SCHEMBL8656134 | 0.62 | ALDH1A1 (0.47) | LMNAMCOLN3ALDH1A1L3MBTL1POLB | |
| SCHEMBL25606172 | 0.62 | CDC25A (0.35) | LMNAMCOLN3ALDH1A1L3MBTL1CDC25A | |
| SCHEMBL12180573 | 0.61 | BRPF1 (0.38) | ALDH1A1L3MBTL1POLBKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081508-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-04-23 | — | — | WO | disclosed |