SCHEMBL29348259

SCHEMBL29348259

CCN1C(=O)OCCC12CC2

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 2/20 0.32
NAAA Q02083 1/20 0.31
LMNA P02545 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23469844 0.82 PIK3CD (0.33) PIK3CD
SCHEMBL27398082 0.80 LMNA (0.34) PIK3CDNAAALMNACYP2C9
SCHEMBL29348266 0.74 PIK3CD (0.32) PIK3CD
SCHEMBL7406886 0.71 CHRM2 (0.39) PIK3CD
SCHEMBL16190004 0.68 P2RX7 (0.37)
SCHEMBL13270729 0.67
SCHEMBL14401481 0.67 PIK3CD (0.44) PIK3CD
SCHEMBL14085832 0.64 PIK3CD (0.46) PIK3CDLMNACYP2C9
SCHEMBL21297462 0.63 USP19 (0.37) PIK3CD
SCHEMBL16268563 0.62 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151547-A1 TARGETED DEGRADATION OF VAV1 MONTE ROSA THERAPEUTICS, INC. (US) 2024-07-18 WO disclosed