Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348226 | 1.00 | PDE3B (0.47) | PDE3BPDE3ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL7349339 | 0.80 | PDE3B (0.49) | PDE3BPDE3ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL13091065 | 0.75 | TSHR (0.54) | PDE3BPDE3ATSHRALDH1A1HTT | |
| SCHEMBL21483647 | 0.73 | PDE3B (0.53) | PDE3BPDE3ATSHRALDH1A1HTT | |
| SCHEMBL23424250 | 0.72 | BRD4 (0.33) | ALDH1A1HTTBRD4 | |
| SCHEMBL29348208 | 0.72 | CYP11B1 (0.41) | TSHRALDH1A1HTT | |
| SCHEMBL23424316 | 0.68 | CHRNB4 (0.33) | HTTBRD4 | |
| SCHEMBL21486491 | 0.66 | TSHR (0.47) | PDE3BPDE3ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL8029140 | 0.65 | CASP3 (0.41) | PDE3BPDE3AALDH1A1NPSR1 | |
| SCHEMBL7341476 | 0.65 | PDE3B (1.00) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |