SCHEMBL29348293

SCHEMBL29348293

O=C1Cn2ccnc2CN1I

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29348300 0.73 USP19 (0.33)
SCHEMBL29348206 0.73 IDH1 (0.30)
SCHEMBL23349325 0.69
SCHEMBL18123343 0.68 SCD (0.36) ADRA1DADRA1A
SCHEMBL23065253 0.65 ADRA1D (0.31) ADRA1DADRA1A
SCHEMBL19722677 0.62 SCD (0.49)
SCHEMBL2664632 0.60 SCD (0.36) ADRA1DADRA1A
SCHEMBL3747911 0.60 SCD (0.39) ADRA1DADRA1A
SCHEMBL22916888 0.60 SCD (0.36) ADRA1DADRA1A
SCHEMBL30210548 0.59 GAA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151547-A1 TARGETED DEGRADATION OF VAV1 MONTE ROSA THERAPEUTICS, INC. (US) 2024-07-18 WO disclosed