Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226591 | 0.77 | ADRA1A (0.31) | — | |
| SCHEMBL29348293 | 0.73 | ADRA1D (0.31) | — | |
| SCHEMBL29348300 | 0.72 | USP19 (0.33) | — | |
| SCHEMBL9834032 | 0.70 | MAPT (0.41) | — | |
| SCHEMBL13290569 | 0.70 | MAPT (0.41) | — | |
| SCHEMBL13290579 | 0.70 | MAPT (0.41) | — | |
| SCHEMBL19164218 | 0.69 | ADRA1A (0.31) | — | |
| SCHEMBL13513137 | 0.67 | — | — | |
| SCHEMBL6510074 | 0.67 | HRH1 (0.32) | IDH1 | |
| SCHEMBL23349325 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |