Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13533992 | 0.80 | KDM4E (0.50) | RXRAGRIN1GRIN2BALDH1A1CYP1A2 | |
| SCHEMBL20280911 | 0.79 | HRH1 (0.46) | RXRAGRIN1GRIN2BALDH1A1CYP2C19 | |
| SCHEMBL12394763 | 0.79 | HRH4 (0.40) | RXRAGRIN1GRIN2BALDH1A1CYP1A2 | |
| SCHEMBL6638892 | 0.79 | KDM4E (0.38) | RXRAGRIN1GRIN2BTAS1R3TAS1R1 | |
| SCHEMBL18799858 | 0.77 | LMNA (0.40) | RXRAGRIN1GRIN2BCYP1A2NOS1 | |
| SCHEMBL20656683 | 0.76 | CYP1A2 (0.56) | ALDH1A1CYP1A2DYRK1ASMN1; SMN2HRH3 | |
| SCHEMBL2547950 | 0.76 | KCNH2 (0.42) | CYP1A2KDM4ELMNACYP3A4TSHR | |
| SCHEMBL11994370 | 0.76 | CYP1A2 (0.46) | RXRAGRIN1GRIN2BALDH1A1CYP1A2 | |
| SCHEMBL19821720 | 0.75 | KDM4E (0.35) | RXRAGRIN1GRIN2BALDH1A1CYP1A2 | |
| SCHEMBL3507581 | 0.74 | TLR9 (0.38) | RXRAGRIN1GRIN2BALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |