Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 5/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179075 | 0.96 | GAA (0.34) | PER2FGFR1FGFR3CHRNA7GAA | |
| SCHEMBL28355124 | 0.78 | PER2 (0.42) | PER2GAAL3MBTL1 | |
| SCHEMBL10511260 | 0.76 | FKBP1A (0.43) | — | |
| SCHEMBL10511269 | 0.76 | FKBP1A (0.43) | — | |
| SCHEMBL10511265 | 0.76 | FKBP1A (0.43) | — | |
| SCHEMBL10509709 | 0.75 | APEX1 (0.44) | PER2 | |
| SCHEMBL10509699 | 0.75 | APEX1 (0.44) | PER2 | |
| SCHEMBL10509705 | 0.75 | APEX1 (0.44) | PER2 | |
| SCHEMBL9273034 | 0.74 | GBA1 (0.32) | PER2 | |
| SCHEMBL13507401 | 0.74 | MAPK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |