Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.39 |
| ▸ | JAK1 | P23458 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068101 | 1.00 | PRKAB2 (0.39) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL29348412 | 0.85 | CREBBP (0.48) | DDB1CRBNHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL31068121 | 0.84 | CREBBP (0.47) | DDB1CRBNNPC1HPGDSMN1; SMN2 | |
| SCHEMBL29348783 | 0.84 | CREBBP (0.47) | DDB1CRBNNPC1HPGDSMN1; SMN2 | |
| SCHEMBL31068261 | 0.83 | DDB1 (0.47) | DDB1CRBNGSPT1 | |
| SCHEMBL29348711 | 0.83 | DDB1 (0.47) | DDB1CRBNGSPT1 | |
| SCHEMBL29348473 | 0.83 | KMT2A (0.41) | DDB1CRBNNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31068201 | 0.83 | KMT2A (0.41) | DDB1CRBNNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29348399 | 0.82 | HRH3 (0.45) | DDB1CRBNHRH3GSPT1 | |
| SCHEMBL31068190 | 0.81 | HPGD (0.39) | DDB1CRBNHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |