Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068121 | 1.00 | CREBBP (0.47) | CREBBPBRD4CRBNDDB1HPGD | |
| SCHEMBL29348412 | 0.99 | CREBBP (0.48) | CREBBPBRD4CRBNDDB1HPGD | |
| SCHEMBL29348447 | 0.86 | HSP90AA1 (0.40) | CREBBPBRD4CRBNDDB1HPGD | |
| SCHEMBL31068305 | 0.86 | HSP90AA1 (0.40) | CREBBPBRD4CRBNDDB1HPGD | |
| SCHEMBL31068259 | 0.86 | CRBN (0.44) | CREBBPBRD4CRBNDDB1ALDH1A1 | |
| SCHEMBL31637574 | 0.86 | CRBN (0.44) | CREBBPBRD4CRBNDDB1ALDH1A1 | |
| SCHEMBL31068201 | 0.84 | KMT2A (0.41) | CRBNDDB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL31068101 | 0.84 | PRKAB2 (0.39) | CRBNDDB1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29348473 | 0.84 | KMT2A (0.41) | CRBNDDB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL29348461 | 0.84 | PRKAB2 (0.39) | CRBNDDB1HPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |