Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 6/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068156 | 1.00 | DDB1 (0.44) | DDB1CRBNCYP11B1CYP11B2CYP2C9 | |
| SCHEMBL31068335 | 0.92 | PGR (0.50) | DDB1CRBNCYP11B1CYP11B2PDE3B | |
| SCHEMBL31068353 | 0.90 | DDB1 (0.43) | DDB1CRBNCYP11B1CYP11B2CYP2C9 | |
| SCHEMBL29348683 | 0.88 | DDB1 (0.42) | DDB1CRBNCYP11B1CYP11B2CYP2C9 | |
| SCHEMBL31068108 | 0.88 | DDB1 (0.42) | DDB1CRBNCYP11B1CYP11B2CYP2C9 | |
| SCHEMBL31068273 | 0.84 | DDB1 (0.43) | DDB1CRBNPGRGRIA1CACNG8 | |
| SCHEMBL38664518 | 0.84 | DDB1 (0.40) | DDB1CRBNCYP11B1CYP11B2CYP2C9 | |
| SCHEMBL29348693 | 0.84 | DDB1 (0.43) | DDB1CRBNPGRGRIA1CACNG8 | |
| SCHEMBL31068286 | 0.84 | CREBBP (0.44) | DDB1CRBNMAPTBRD4CREBBP | |
| SCHEMBL29348696 | 0.84 | CREBBP (0.44) | DDB1CRBNMAPTBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |