Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 13/20 | 0.44 |
| ▸ | BRD4 | O60885 | 11/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068286 | 1.00 | CREBBP (0.44) | CREBBPBRD4DDB1CRBNLMNA | |
| SCHEMBL29348689 | 0.84 | DDB1 (0.44) | CREBBPBRD4DDB1CRBNMAPT | |
| SCHEMBL31068156 | 0.84 | DDB1 (0.44) | CREBBPBRD4DDB1CRBNMAPT | |
| SCHEMBL31068353 | 0.83 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL31068335 | 0.83 | PGR (0.50) | CREBBPBRD4DDB1CRBN | |
| SCHEMBL29348693 | 0.82 | DDB1 (0.43) | CREBBPBRD4DDB1CRBN | |
| SCHEMBL31068273 | 0.82 | DDB1 (0.43) | CREBBPBRD4DDB1CRBN | |
| SCHEMBL29348683 | 0.82 | DDB1 (0.42) | DDB1CRBNLMNAMAPT | |
| SCHEMBL31068108 | 0.82 | DDB1 (0.42) | DDB1CRBNLMNAMAPT | |
| SCHEMBL38664518 | 0.80 | DDB1 (0.40) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |