Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | RGS4 | P49798 | 1/20 | 0.33 |
| ▸ | RGS8 | P57771 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27871648 | 0.84 | MGLL (0.56) | MGLLELANEF2CTSGCMA1 | |
| SCHEMBL28136703 | 0.74 | MGLL (0.37) | MGLLELANEF2CTSGCMA1 | |
| SCHEMBL9319068 | 0.72 | ELANE (0.41) | MGLLELANEF2CTSGCMA1 | |
| SCHEMBL29819660 | 0.69 | MEN1 (0.42) | MGLLELANEF2CTSGCMA1 | |
| SCHEMBL22430825 | 0.68 | ELANE (0.42) | MGLLELANEF2CTSGCMA1 | |
| SCHEMBL140025 | 0.66 | MGLL (1.00) | MGLLELANEF2CTSGCMA1 | |
| SCHEMBL28424955 | 0.63 | MGLL (0.56) | MGLLELANELMNAALOX5GSK3A | |
| SCHEMBL27631335 | 0.63 | MGLL (0.56) | MGLLLMNAGSK3AGSK3BHPGD | |
| SCHEMBL27427589 | 0.63 | MGLL (0.56) | MGLLLMNAALDH1A1GAAHPGD | |
| SCHEMBL27492832 | 0.63 | MGLL (0.56) | MGLLLMNAGSK3AGSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |