SCHEMBL28136703

SCHEMBL28136703

Cc1ccc(N2C=CC=CC2=C=O)cc1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.37
F2 P00734 1/20 0.35
ELANE P08246 1/20 0.35
CTSG P08311 1/20 0.35
CMA1 P23946 1/20 0.35
CTRC Q99895 1/20 0.35
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29348705 0.74 MGLL (0.48) MGLLF2ELANECTSGCMA1
SCHEMBL9319068 0.66 ELANE (0.41) MGLLF2ELANECTSGCMA1
SCHEMBL27871648 0.65 MGLL (0.56) MGLLF2ELANECTSGCMA1
Hydrochloric Acid SCHEMBL10697466 0.65 ALDH1A1 (0.33) ALDH1A1GAA
SCHEMBL29819660 0.63 MEN1 (0.42) MGLLF2ELANECTSGCMA1
Bromide SCHEMBL27399405 0.63 ALDH1A1 (0.32) MEN1ALDH1A1GAAKMT2A
SCHEMBL22430825 0.61 ELANE (0.42) MGLLF2ELANECTSGCMA1
SCHEMBL12230241 0.57 ACHE (0.50) MGLLF2ELANECTSGCMA1
SCHEMBL21305193 0.56 KDM4E (0.36) MGLLF2ELANECTSGCMA1
SCHEMBL31325944 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661386-A Laminate optical film production method 日东电工株式会社 2017-05-10 CN disclosed