Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28431820 | 0.77 | MGLL (0.60) | MGLLMEN1KMT2AALDH1A1HTT | |
| SCHEMBL28807321 | 0.73 | BCHE (0.56) | MGLLMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL962950 | 0.71 | MGLL (1.00) | MGLLMEN1KMT2AELANEALDH1A1 | |
| SCHEMBL11625350 | 0.70 | KMT2A (0.53) | MGLLMEN1KMT2AELANEPOLB | |
| SCHEMBL8017388 | 0.68 | MEN1 (0.45) | MGLLMEN1KMT2AELANEPOLB | |
| SCHEMBL9623389 | 0.65 | POLB (0.56) | MGLLMEN1KMT2AELANEPOLB | |
| SCHEMBL9432925 | 0.64 | LMNA (0.50) | MGLLMEN1KMT2AELANEPOLB | |
| SCHEMBL21801270 | 0.64 | MGLL (0.73) | MGLLMEN1KMT2AELANEALDH1A1 | |
| Maleic Anhydride SCHEMBL8720485 | 0.63 | MGLL (0.77) | MGLLMEN1KMT2AELANEALDH1A1 | |
| SCHEMBL28424953 | 0.63 | MGLL (0.61) | MGLLALDH1A1ALOX5FAAHALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534631-B | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117534631-A | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-107646855-B | Application of thiazole compound containing piperidine in preparation of bactericide and preparation method thereof | 浙江工业大学 | 2020-07-07 | — | — | CN | disclosed |