Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348443 | 0.81 | DDB1 (0.41) | MTORALDH1A1 | |
| SCHEMBL29348442 | 0.81 | DDB1 (0.41) | MTORALDH1A1 | |
| SCHEMBL29348774 | 0.81 | DDB1 (0.41) | MTORALDH1A1 | |
| SCHEMBL29348526 | 0.79 | ROCK2 (0.35) | CNR2SRD5A1 | |
| SCHEMBL29348200 | 0.78 | F10 (0.36) | — | |
| SCHEMBL29348769 | 0.78 | F10 (0.36) | — | |
| SCHEMBL29348489 | 0.77 | CD274 (0.33) | CNR2 | |
| SCHEMBL29348519 | 0.77 | HCRTR2 (0.38) | CNR2 | |
| SCHEMBL29349028 | 0.76 | CNR2 (0.36) | CNR2SRD5A1 | |
| SCHEMBL29348360 | 0.75 | PDCD1LG2 (0.39) | ALDH1A1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |