SCHEMBL29348200

SCHEMBL29348200

O=C1CC[C@@H](c2cccc(-c3ccc(-n4ccccc4=O)cc3)c2Cl)C(O)N1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F10 P00742 18/20 0.36
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
PAK1 Q13153 1/20 0.33
F2 P00734 1/20 0.33
PLAT P00750 1/20 0.33
KLKB1 P03952 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29348769 1.00 F10 (0.36) F10SLC6A2SLC6A4SLC6A3PAK1
SCHEMBL29348413 0.83 CD274 (0.37) KLKB1
SCHEMBL29348448 0.82 FFAR2 (0.34)
SCHEMBL29349028 0.79 CNR2 (0.36)
SCHEMBL29348526 0.79 ROCK2 (0.35)
SCHEMBL29348199 0.79 DDB1 (0.45) F10SLC6A2SLC6A4SLC6A3
SCHEMBL29348198 0.79 DDB1 (0.45) F10SLC6A2SLC6A4SLC6A3
SCHEMBL29348202 0.79 DDB1 (0.45) F10SLC6A2SLC6A4SLC6A3
SCHEMBL29348204 0.78 F10 (0.37) F10SLC6A2SLC6A4SLC6A3PAK1
SCHEMBL29348776 0.78 CNR2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151547-A1 TARGETED DEGRADATION OF VAV1 MONTE ROSA THERAPEUTICS, INC. (US) 2024-07-18 WO disclosed