Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348519 | 0.88 | HCRTR2 (0.38) | CD274PDCD1GRM2PDCD1LG2HCRTR1 | |
| SCHEMBL29348513 | 0.79 | GRM2 (0.37) | CD274PDCD1GRM2PDCD1LG2HCRTR1 | |
| SCHEMBL29348776 | 0.77 | CNR2 (0.32) | CNR2 | |
| SCHEMBL29348603 | 0.77 | GRM2 (0.35) | CD274PDCD1GRM2PDCD1LG2 | |
| SCHEMBL29348345 | 0.74 | CD274 (0.34) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29348526 | 0.73 | ROCK2 (0.35) | CD274PDCD1LG2CNR2 | |
| SCHEMBL29348413 | 0.73 | CD274 (0.37) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29348360 | 0.72 | PDCD1LG2 (0.39) | CD274PDCD1LG2 | |
| SCHEMBL29348769 | 0.71 | F10 (0.36) | — | |
| SCHEMBL29348448 | 0.71 | FFAR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |