Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | CTRC | Q99895 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15448368 | 0.89 | DRD2 (0.55) | DRD2DRD3F2ELANECTSG | |
| SCHEMBL4711615 | 0.85 | MAPT (0.44) | DRD2DRD3F2GAAHTT | |
| SCHEMBL29348779 | 0.84 | MEN1 (0.38) | DRD2DRD3F2RAB9ANPC1 | |
| SCHEMBL6362778 | 0.83 | MEN1 (0.61) | DRD2DRD3RAB9ANPC1MEN1 | |
| SCHEMBL25685276 | 0.81 | MGLL (0.43) | DRD2DRD3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL20057689 | 0.81 | DRD2 (0.36) | DRD2DRD3GAASMN1; SMN2RAB9A | |
| SCHEMBL20313983 | 0.81 | GAA (0.49) | DRD2DRD3GAAHTTRAB9A | |
| SCHEMBL14337562 | 0.80 | DRD2 (0.48) | DRD2DRD3F2ELANECTSG | |
| SCHEMBL2555563 | 0.80 | HRH3 (0.37) | DRD2DRD3F2RAB9ANPC1 | |
| SCHEMBL21594891 | 0.80 | CHKA (0.50) | DRD2DRD3F2SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |