Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348791 | 0.83 | POLB (0.41) | MGLLMMP13KMT2AALDH1A1POLB | |
| SCHEMBL29348793 | 0.83 | MMP13 (0.53) | FAAHMGLLMMP13KMT2AMMP2 | |
| SCHEMBL29348908 | 0.81 | TNKS (0.39) | FAAHMGLLMMP13KMT2AALDH1A1 | |
| SCHEMBL29348818 | 0.79 | KMT2A (0.53) | MGLLMMP13KMT2AMMP2MMP3 | |
| SCHEMBL24253818 | 0.73 | MMP13 (0.44) | MMP13KMT2AMMP2MMP3MMP9 | |
| SCHEMBL29349005 | 0.72 | MMP13 (0.56) | FAAHMGLLMMP13MMP2MMP3 | |
| SCHEMBL29348930 | 0.71 | MMP13 (0.59) | FAAHMGLLMMP13MMP2MMP3 | |
| SCHEMBL29348913 | 0.71 | KMT2A (0.47) | MGLLMMP13KMT2AALDH1A1POLB | |
| SCHEMBL29348817 | 0.70 | ALDH1A1 (0.41) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL31068314 | 0.69 | MMP13 (0.36) | MMP13MMP2MMP3MMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |