Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348907 | 0.83 | LMNA (0.42) | POLBMAPTHTTLMNAELANE | |
| SCHEMBL29348792 | 0.83 | FAAH (0.36) | POLBALDH1A1MGLLKMT2AMMP13 | |
| SCHEMBL29348793 | 0.83 | MMP13 (0.53) | POLBALDH1A1MGLLKMT2AMMP13 | |
| SCHEMBL29348818 | 0.79 | KMT2A (0.53) | POLBMAPTALDH1A1MGLLTSHR | |
| SCHEMBL8305604 | 0.75 | HTT (0.45) | POLBMAPTHTTLMNAELANE | |
| SCHEMBL29348817 | 0.73 | ALDH1A1 (0.41) | POLBLMNAALDH1A1MMP13 | |
| SCHEMBL24253818 | 0.73 | MMP13 (0.44) | MAPTHTTLMNAALOX5ALDH1A1 | |
| SCHEMBL29349005 | 0.72 | MMP13 (0.56) | POLBALDH1A1MGLLMMP13 | |
| SCHEMBL29348930 | 0.71 | MMP13 (0.59) | POLBALDH1A1MGLLMMP13 | |
| SCHEMBL29348913 | 0.71 | KMT2A (0.47) | POLBMAPTALDH1A1MGLLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |