Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | VEGFA | P15692 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.44 |
| ▸ | F13A1 | P00488 | 2/20 | 0.43 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | TGM1 | P22735 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114519 | 0.86 | VEGFA (0.50) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL30520640 | 0.84 | MEN1 (0.50) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL30584532 | 0.83 | MEN1 (0.49) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL12557699 | 0.83 | KMT2A (0.69) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL1997213 | 0.83 | MEN1 (0.49) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL2933302 | 0.83 | MEN1 (0.49) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL30042412 | 0.83 | MEN1 (0.49) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL18038932 | 0.83 | VEGFA (0.52) | MEN1KMT2AVEGFAEGLN1CHRM2 | |
| SCHEMBL209280 | 0.82 | TBK1 (0.55) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL31298334 | 0.82 | MEN1 (0.51) | MEN1KMT2AATMVEGFAEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229377-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | Wyeth LLC (US) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009076602-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | WYETH (US) | 2009-06-18 | — | — | WO | disclosed |