SCHEMBL29349985

SCHEMBL29349985

CC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)[C@@H](C)O

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 8/20 0.66
▸ IL23R Q5VWK5 1/20 0.61
▸ RAMP3 O60896 1/20 0.61
▸ CALCR P30988 1/20 0.61
▸ NPY2R P49146 7/20 0.60
▸ NPY4R P50391 7/20 0.60
▸ NPY5R Q15761 7/20 0.60
▸ NPY1R P25929 5/20 0.60
▸ KEAP1 Q14145 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29581485 0.97 NPY2R (0.64) TFPIIL23RRAMP3CALCRNPY2R
SCHEMBL29405698 0.89 TFPI (0.70) TFPIIL23RRAMP3CALCRNPY2R
SCHEMBL30495735 0.89 RAMP3 (0.67) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL14479433 0.87 OPRM1 (0.64) TFPIKEAP1
SCHEMBL30607473 0.87 NPY2R (0.63) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL17722482 0.87 TFPI (0.68) TFPI
SCHEMBL30648456 0.86 OPRM1 (0.63) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL31174222 0.86 NPY2R (0.57) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL30712913 0.86 NPY2R (0.64) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL31182450 0.86 NPY2R (0.66) TFPIRAMP3CALCRNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220235320-A1 DISSOLVABLE MICROCARRIERS FOR CULTURING CELLS AND RELATED METHODS CORNING INCORPORATED 2022-07-28 — — US disclosed
US-20220186178-A1 CELL CULTURE ARTICLE AND METHODS THEREOF CORNING INC (US) 2022-06-16 — — US disclosed
US-20220073868-A1 SYSTEMS AND METHODS FOR CULTURING CELLS IN SUSPENSION CORNING INCORPORATED 2022-03-10 — — US disclosed
CN-113966391-A Soluble microcarriers for culturing cells and related methods 康宁股份有限公司 2022-01-21 — — CN disclosed
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