SCHEMBL29405698

SCHEMBL29405698

CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)[C@@H](C)O)C(C)C

nearest known ligand 0.72

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 7/20 0.70
▸ RAMP3 O60896 3/20 0.68
▸ CALCR P30988 3/20 0.68
▸ NPY2R P49146 7/20 0.65
▸ NPY4R P50391 7/20 0.65
▸ NPY5R Q15761 7/20 0.65
▸ NPY1R P25929 5/20 0.65
▸ IL23R Q5VWK5 1/20 0.64
▸ KDM1A O60341 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404705 0.91 RAMP3 (0.70) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL30906377 0.90 NPY2R (0.71) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL29349985 0.89 TFPI (0.66) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL29533414 0.89 TFPI (0.70) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL8814395 0.89 NPY2R (0.71) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL30906497 0.88 NPY2R (0.69) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL29361709 0.88 TFPI (0.71) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL31182566 0.88 TFPI (0.68) TFPICALCRNPY2RNPY4RNPY5R
SCHEMBL30541676 0.88 TFPI (0.68) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL30906464 0.88 NPY2R (0.70) TFPIRAMP3CALCRNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
WO-2025245188-A2 METHODS OF TREATING LIVER STEATOSIS AND NON-ALCOHOLIC FATTY LIVER DISEASE FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2025-11-27 — — WO disclosed
US-20250304916-A1 METHODS AND COMPOSITIONS FOR GENERATING VASCULAR LEPTOMENINGEAL CELLS TRAILHEAD BIOSYSTEMS INC (US) 2025-10-02 — — US disclosed
US-20250295587-A1 COMPLEX LIPID NANOPARTICLES ENCAPSULATING POLYPEPTIDES AND USES THEREOF SAIL BIOMEDICINES, INC. 2025-09-25 — — US disclosed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 — — US disclosed
EP-4529468-A1 FORMULATION OF API'S AND EXCIPIENT'S IN AN ICELL VIA HYDROPHOBIC ION PAIRING Danmarks Tekniske Universitet (DK) 2025-04-02 — — EP disclosed
EP-4529477-A1 POROUS EXPANDING BIOCOMPATIBLE SCAFFOLDS Danmarks Tekniske Universitet (DK) 2025-04-02 — — EP disclosed
US-20220306577-A1 THIOSEMICARBAZATES AND USES THEREOF FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-29 — — US disclosed
US-20220288150-A1 PLANT MESSENGER PACKS ENCAPSULATING POLYPEPTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-09-15 — — US disclosed
US-11440881-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-13 — — US disclosed
US-20220282239-A1 MODIFICATIONS OF PEPTIDE COMPOSITIONS TO INCREASE STABILITY AND DELIVERY EFFICIENCY KAI PHARMACEUTICALS, INC. 2022-09-08 — — US disclosed
US-20220273824-A1 CELL PENETRATING PEPTIDE FUNCTIONALIZED PERFLUOROCARBON NANOEMULSION COMPOSITIONS AND METHODS FOR IMAGING CELL POPULATIONS CALIFORNIA, THE REGENTS OF THE UNIVERSITY OF 2022-09-01 — — US disclosed
US-11414405-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-08-16 — — US disclosed
US-20220152139-A1 PLANT MESSENGER PACKS ENCAPSULATING POLYPEPTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-05-19 — — US disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM TFPI 2710/4885RAMP3 1895/4885CALCR 1359/4885
US-11440881-B2 Thiosemicarbazates and uses thereof TST, ABAT, AADAC TFPI 1882/4885RAMP3 803/4885CALCR 1707/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS TFPI 2300/4885RAMP3 965/4885CALCR 2542/4885
US-11414405-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM TFPI 2710/4885RAMP3 1895/4885CALCR 1359/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 TFPI 3459/4885RAMP3 1293/4885CALCR 1358/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 TFPI 1686/4885RAMP3 737/4885CALCR 1795/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT TFPI 2392/4885RAMP3 1187/4885CALCR 1581/4885
US-20220306577-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC TFPI 1882/4885RAMP3 803/4885CALCR 1707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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