Galidesivir

Galidesivir

SCHEMBL29351502

Nc1ncnc2c([C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)c[nH]c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

Lrep

The experimentally established mechanism targets of Galidesivir. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNP P00491 2/20 1.00
MTAP Q13126 15/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Galidesivir SCHEMBL17117187 1.00 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL16884051 1.00 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL29055146 1.00 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL23102311 1.00 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL15717852 1.00 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL25424734 1.00 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL12468816 1.00 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL17760735 1.00 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL15718263 1.00 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL4838048 0.99 PNP (0.97) PNPMTAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20260139860-A1 PRODUCTS OF MANUFACTURE FOR THE TREATMENT, PREVENTION AND AMELIORATION OF MICROBIAL INFECTIONS CENTRE FOR DIGESTIVE DISEASES (AU) 2026-05-21 US claimed
US-20260102422-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-04-16 US claimed
EP-4714452-A1 METHODS FOR TREATING SARS COV-2 INFECTIONS Gilead Sciences, Inc. (US) 2026-03-25 EP claimed
EP-4704881-A2 HUMORAL MODULATION IN VACCINATED AND VIRALLY INFECTED SUBJECTS WITH GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF) Partner Therapeutics, Inc. (US) 2026-03-11 EP claimed
EP-4704880-A1 VIRAL INFECTION MODULATION IN VACCINATED SUBJECTS TREATED WITH GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF) Partner Therapeutics, Inc. (US) 2026-03-11 EP claimed
US-12551550-B2 Compositions and vaccines for treating and/or preventing coronavirus variant infections and methods of using the same ENGENEIC MOLECULAR DELIVERY PTY LTD (AU) 2026-02-17 US claimed
EP-4680248-A1 PRODUCTS OF MANUFACTURE AND THERAPEUTIC COMPOSITIONS FOR TREATING, AMELIORATING OR PREVENTING VIRAL INFECTIONS AND METHODS FOR MAKING AND USING THEM Topelia Aust Limited (ACN 652 771 670) (AU) 2026-01-21 EP claimed
EP-4676527-A2 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CRIMEAN CONGO HEMORRHAGIC FEVER VIRUS SVF Vaccines AB (SE) 2026-01-14 EP claimed
EP-4673157-A2 COMPOSITIONS FOR MODULATING GUT MICROFLORA POPULATIONS, TREATMENT OF DYSBIOSIS AND DISEASE PREVENTION, AND METHODS FOR MAKING AND USING SAME Persephone Biosciences, Inc. (US) 2026-01-07 EP claimed
WO-2022053993-A2 TREATMENTS FOR SARS-COV-2 INFECTION (COVID-19) MYLAN LABORATORIES LIMITED (IN) 2022-03-17 WO claimed
WO-2022051650-A1 HUMAN MONOCLONAL ANTIBODIES TO SARS-COV-2 AND USE THEREOF THE UAB RESEARCH FOUNDATION (US) 2022-03-10 WO claimed
EP-3963087-A1 IDENTIFICATION AND ANALYSIS OF MICROBIAL SAMPLES BY RAPID INCUBATION AND NUCLEIC ACID ENRICHMENT Illumina Inc (US) 2022-03-09 EP claimed
WO-2022046642-A1 COMPOUNDS AND COMPOSITIONS FOR DISRUPTING PROGRAMMED RIBOSOMAL FRAMESHIFTING YALE UNIVERSITY (US) 2022-03-03 WO claimed
WO-2022047311-A1 COMPUTERIZED DECISION SUPPORT TOOL AND MEDICAL DEVICE FOR RESPIRATORY CONDITION MONITORING AND CARE PFIZER INC. (US) 2022-03-03 WO claimed
EP-3953361-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF COVID-19 Pfizer Inc. (US) 2022-02-16 EP claimed
WO-2022029334-A1 COMBINATION THERAPIES FOR TREATING CORONAVIRUS INFECTION GBIOTECH S.À.R.L. (CH) 2022-02-10 WO claimed
US-20220031709-A1 INHIBITION OF MICROSOMAL PROSTAGLANDIN E2 (PGE2) SYNTHASE-1 (MPGES-1) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2022-02-03 US claimed
CN-113993518-A Systemic isoxazoline repellents for the treatment or prevention of vector-transmitted and viral diseases 塔苏斯制药有限公司 2022-01-28 CN claimed
CN-113952457-A Application of termitimide or pharmaceutical composition containing termitimide in resisting coronavirus 欣凯医药化工中间体(上海)有限公司 2022-01-21 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220031709-A1 INHIBITION OF MICROSOMAL PROSTAGLANDIN E2 (PGE2) SYNTHASE-1 (MPGES-1) PTGES, PTGS1, PTGES2 PNP 724/4885MTAP 980/4885
US-20260102422-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO SARS1, ITK, SLC43A1 PNP 25/4885MTAP 23/4885
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 PNP 1440/4885MTAP 3703/4885
US-12551550-B2 Compositions and vaccines for treating and/or preventing coronavirus variant infections and methods of using the same CACNG1, CACNG2, CACNG7 PNP 2090/4885MTAP 1518/4885
US-20260139860-A1 PRODUCTS OF MANUFACTURE FOR THE TREATMENT, PREVENTION AND AMELIORATION OF MICROBIAL INFECTIONS ACE, MAVS, SARS1 PNP 2061/4885MTAP 1906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.