SCHEMBL29352155

SCHEMBL29352155

CCCCCCOC(F)(F)C(F)F

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
DNM1 Q05193 1/20 0.36
THRB P10828 2/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34
USP2 O75604 1/20 0.34
PLA2G2C Q5R387 1/20 0.34
LPAR3 Q9UBY5 4/20 0.33
CA1 P00915 4/20 0.33
CA2 P00918 4/20 0.33
CA9 Q16790 4/20 0.33
LPAR2 Q9HBW0 3/20 0.33
LPAR1 Q92633 2/20 0.33
NAAA Q02083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29760638 1.00 CES2 (0.41) CES2CES1DNM1THRBTSHR
SCHEMBL29691410 1.00 CES2 (0.41) CES2CES1DNM1THRBTSHR
SCHEMBL11995881 0.98 CES2 (0.38) CES2CES1DNM1THRBTSHR
SCHEMBL2517597 0.91 ADRB2 (0.35) CES2CES1TSHR
SCHEMBL10985168 0.85 FAAH (0.33) CES2CES1TSHRLPAR3LPAR2
SCHEMBL29760630 0.83 CES2 (0.39) CES2CES1DNM1THRBTSHR
SCHEMBL29760710 0.83 CES2 (0.39) CES2CES1DNM1THRBTSHR
SCHEMBL2522757 0.81
SCHEMBL21069189 0.81
SCHEMBL11995880 0.81 CES2 (0.36) CES2CES1DNM1PLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3543310-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-32 CHEMOURS CO FC LLC (US) 2024-07-03 EP disclosed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP disclosed
EP-2749623-B2 Method for replacing a high GWP refrigerant in a refrigeration, air-conditioning, or heat pump apparatus CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
EP-3309233-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-152A CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
EP-4269452-A1 METHOD FOR PRODUCING FLUOROPOLYMER DAIKIN INDUSTRIES, LTD. (JP) 2023-11-01 EP disclosed
US-20230331886-A1 METHOD FOR PRODUCING FLUOROPOLYMER DAIKIN INDUSTRIES, LTD., (JP) 2023-10-19 US disclosed
US-11674067-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2023-06-13 US disclosed
US-20220389298-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
US-20220389297-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
EP-4074807-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN The Chemours Company FC, LLC (US) 2022-10-19 EP disclosed
WO-2022138768-A1 METHOD FOR PRODUCING FLUOROPOLYMER ダイキン工業株式会社 2022-06-30 WO disclosed
EP-1985680-B2 Composition comprising a HFC-1234ze isomer CHEMOURS CO FC LLC (US) 2022-06-29 EP disclosed
CN-109971430-B Compositions comprising fluoroolefins 科慕埃弗西有限公司 2022-02-18 CN disclosed
CN-109971429-B Compositions comprising fluoroolefins 科慕埃弗西有限公司 2022-02-18 CN disclosed
CN-109897606-B Compositions comprising fluoroolefins 科慕埃弗西有限公司 2022-02-11 CN disclosed
CN-113956851-A Compositions comprising fluoroolefins 科慕埃弗西有限公司 2022-01-21 CN disclosed