Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596029 | 0.94 | ADH1B (0.47) | TAS1R3TAS1R1TAS1R2CA1CA2 | |
| SCHEMBL9683898 | 0.94 | ADH1B (0.47) | TAS1R3TAS1R1TAS1R2CA1CA2 | |
| SCHEMBL27586792 | 0.92 | ADH1B (0.50) | TAS1R3TAS1R1TAS1R2CA1MLYCD | |
| SCHEMBL11681448 | 0.92 | ADH1B (0.50) | TAS1R3TAS1R1TAS1R2CA1MLYCD | |
| SCHEMBL9252302 | 0.92 | ADH1B (0.50) | TAS1R3TAS1R1TAS1R2CA1MLYCD | |
| SCHEMBL292612 | 0.86 | — | — | |
| SCHEMBL9555396 | 0.83 | BLM (0.41) | TAS1R3TAS1R1TAS1R2CA1MLYCD | |
| Dimethylamine SCHEMBL27603501 | 0.83 | ALDH1A1 (0.43) | TAS1R3TAS1R1TAS1R2MEN1FAAH | |
| SCHEMBL6841356 | 0.83 | GABRR1 (0.37) | TAS1R3TAS1R1TAS1R2DPP7DPP8 | |
| Dimethylamine SCHEMBL27595612 | 0.81 | ALDH1A1 (0.42) | TAS1R3TAS1R1TAS1R2MEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461327-A | Spiro urea derivatives | 爱杜西亚药品有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-110546566-B | Positive photosensitive siloxane composition and cured film formed using same | 默克专利有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-115461327-A | Spiro urea derivatives | 爱杜西亚药品有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-114401956-A | Substituted N-phenyluracils, their salts and their use as herbicides | 拜耳公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-107108851-B | Dynamic urea linkage of polymers | 伊利诺伊大学董事会 | 2021-01-08 | — | — | CN | disclosed |
| US-20200239622-A1 | DYNAMIC UREA BONDS FOR POLYMERS | NATIONAL SCIENCE FOUNDATION | 2020-07-30 | — | — | US | disclosed |
| US-20170327627-A1 | DYNAMIC UREA BONDS FOR POLYMERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2017-11-16 | — | — | US | disclosed |
| WO-2016069582-A1 | DYNAMIC UREA BONDS FOR POLYMERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-06 | — | — | WO | disclosed |
| US-8158790-B2 | Cyclic amine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-04-17 | — | — | US | disclosed |
| EP-2036896-B1 | CYCLIC AMINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2012-03-14 | — | — | EP | disclosed |
| EP-2036896-A1 | CYCLIC AMINE COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1085009-B1 | INDAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| EP-0934296-B1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6486178-B1 | Indane derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1085009-A1 | INDAN DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-6066631-A | Chroman derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| WO-2000012492-A1 | BENZOXAZINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |
| CN-1226243-A | Benzodihydropyran derivative | NISSAN CHEMICAL IND LTD (JP) | 1999-08-18 | — | — | CN | disclosed |
| EP-0934296-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004542-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327627-A1 | DYNAMIC UREA BONDS FOR POLYMERS | KDM4D, KDM4A, UMPS | TAS1R3 1593/4885TAS1R1 2006/4885TAS1R2 2154/4885 |
| US-20200239622-A1 | DYNAMIC UREA BONDS FOR POLYMERS | KDM4D, KDM4A, UMPS | TAS1R3 1593/4885TAS1R1 2006/4885TAS1R2 2154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.